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cystatin 2 (cystatin-SA, cystatin S5, CST2)
Function: thiol protease inhibitor
Structure: belongs to the cystatin family
Compartment: secreted
Expression:
- only expressed in submandibular gland & parotid gland
General
cystatin
Properties
SIZE: entity length = 141 aa
MW = 16 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-20}
glycine residue {32}
Secondary area of contact {76-80}
cysteine residue {C94}
MODIFICATION: cysteine residue {C104}
cysteine residue {C104}
MODIFICATION: cysteine residue {C94}
cysteine residue {C118}
MODIFICATION: cysteine residue {C138}
cysteine residue {C138}
MODIFICATION: cysteine residue {C118}
INHIBITS: cysteine proteinase
Database Correlations
OMIM 123856
UniProt P09228
Pfam PF00031
Entrez Gene 1470
Kegg hsa:1470
References
- UniProt :accession P09228
- OMIM :accession 123856