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cylicin-1; Cylicin I; multiple-band polypeptide I (CYLC1, CYL, CYL1)
Function:
- possible architectural role during spermatogenesis
- may be involved in spermatid differentiation
Compartment:
- cytoplasm, cytoskeleton, perinuclear theca, calyx
- sperm head cytoskeletal structure
Expression:
- testis
- specific to late spermatogenesis
General
cytoskeletal protein
phosphoprotein
Properties
SIZE: entity length = 651 aa
MW = 74 kD
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: Tyr phosphorylation site {Y104}
consensus repeat {278-305}
consensus repeat {306-342}
consensus repeat {343-379}
consensus repeat {380-417}
MOTIF: Ser phosphorylation site {S406}
Ser phosphorylation site {S409}
Ser phosphorylation site {S411}
consensus repeat {418-453}
consensus repeat {454-491}
consensus repeat {492-531}
consensus repeat {532-553}
MOTIF: domain {532-553}
Ser phosphorylation site {S541}
Thr phosphorylation site {T543}
Ser phosphorylation site {S545}
Ser phosphorylation site {S548}
proline-rich region
SITE: 601-651
MOTIF: proline residue (SEVERAL)
Database Correlations
OMIM 603121
UniProt P35663
Entrez Gene 1538
Kegg hsa:1538
References
UniProt :accession P35663