cyclophilin

A class of immunophilins that bind to the immunosuppressant cyclosporin A.

Specific

cyclophilin A (cyclosporin A-binding protein A, peptidyl-prolyl cis-trans isomerase A, CypA, PPIA) cyclophilin B (peptidyl-prolyl cis-trans isomerase B, S-cyclophilin, CypB, PPIB, SCYLP, CYP-S) cyclophilin C; peptidyl-prolyl cis-trans isomerase C cyclophilin D (cyclophilin 40, 40 kD peptidyl-prolyl cis-trans isomerase, PPID, CYP40, CYPD) cyclophilin E (cyclophilin 3, 33kD peptidyl-prolyl cis-trans isomerase, cyclophilin 33, rotamase E, PPIE, CYP33) cyclophilin F (cyclophilin 3, mitochondrial peptidyl-prolyl cis-trans isomerase, PPIF, CYP3) cyclophilin G (peptidyl-prolyl cis-trans isomerase G, PPIase G, rotamase G, Clk-associating RS-cyclophilin, CARS-cyclophilin, CARS-Cyp, SR-cyclophilin, SRcyp, CASP10, PPIG) cyclophilin H (peptidyl-prolyl cis-trans isomerase H, PPIase H, rotamase H, U-snRNP-associated cyclophilin SnuCyp-20, USA-CYP, small nuclear ribonucleoprotein [snRNP] particle-specific cyclophilin H, PPIH, CYP20, CYPH) cyclophilin-related protein (NK-tumor recognition protein, NKTR) peptidyl-prolyl cis-trans isomerase A-like 4H; PPIase A-like 4H (PPIAL4H) peptidyl-prolyl cis-trans isomerase SDCCAG10; serologically defined colon cancer antigen 10; antigen NY-CO-10 (SDCCAG10, CWC27) peptidyl-prolyl cis-trans isomerase-like 2 (PPIase, rotamase, ryclophilin-60, cyclophilin-like protein Cyp-60, PPIL2) peptidyl-prolyl cis-trans isomerase-like 3 (PPIase, Rotamase, cyclophilin-like protein PPIL3, cyclophilin J, CyPJ, PPIL3) peptidyl-prolyl cis-trans isomerase-like 6 (PPIase, rotamase, cyclophilin-like protein PPIL6, PPIL6) peptidylprolyl cis-trans isomerase A-like 4; PPIase A-like 4; chromosome 1-amplified sequence 2; COAS-2 (PPIAL4, COAS2, PPIAL4A) rhodopsin cyclophilin or Nina-A protein

Properties

MOTIF: active site

References

Ku Tai et al Science 256:1315 1992