cGMP-gated channel

Function: - the channel is maintained in an open state by relatively low-affinity interactions between cGMP & the channel because of the unusually high levels of cGMP found in photoreceptor cells

General

Ca+2 channel Na+ channel

Properties

SIZE: MW = 76-79 kD COMPARTMENT: plasma membrane CELL: rod WITHIN: retina cone WITHIN: fovea centralis epithelial cell WITHIN: olfactory epithelium MOTIF: membrane region cGMP-binding site ION-PERMEABILITY: Na+

References

- Lincoln TM, Cornwell TL. Intracellular cyclic GMP receptor proteins. FASEB J. 1993 Feb 1;7(2):328-38. Review. PMID: 7680013