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curare
An extract of plants, Strychnos toxifera & other species & Chondodendron tomentosum. Alkoloids present in the extract, curarine from Strychnos & tubocurarine from Chondodendron induce non-depolarizing paralysis at the neuromuscular junction after intravenous injection by competitive inhibition of nicotinic receptors.
General
pharmacologic combination
neuromuscular blocker (paralyzing agent)
References
- Stedman's Medical Dictionary 27th ed, Williams &
Wilkins, Baltimore, 1999
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996 pg 178