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cosyntropin (Cortrosyn)

Indications: - cosyntropin-stimulation test - aid in diagnosis of adrenal insufficiency - infantile spasms [2] Dosage: 0.25 mg IV or IM over 2 minutes Adverse effects: hypersensitivity reactions Drug interactions: 1) test does not interact with prednisone, dexamethasone or beclomethasone 2) cortisone & hydrocortisone may cause high baseline cortisol & paradoxical decrease in cortisol following administration of cosyntropin 3) estrogens cause elevated baseline cortisol, but normal incremental response to cosyntropin should occur 4) spironolactone may cause high cortisol levels to be reported when fluorometric analysis is used

Related

cosyntropin (ACTH, Cortrosyn) stimulation test (delta cortisol test)

General

endocrine agent peptide

Properties

MISC-INFO: elimination route LIVER

References

  1. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  2. Deprecated Reference