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cortistatin
Function:
1) binds to all human somatostatin receptor subtypes
2) coricostatin-14 may be ligand for MRGPRX2 (Mas-related G-protein coupled receptor member X2)
3) sleep regulation locomotor activity
4) cortical function
Compartment: secreted
Expression:
- expressed in a subset of GABAergic cells in cortex & hippocampus
Related
somatostatin receptor
General
secreted protein
Properties
COMPARTMENT: extracellular compartment
MOTIF: cysteine residue {C93}
MODIFICATION: cysteine residue {C104}
cysteine residue {C104}
MODIFICATION: cysteine residue {C93}
Database Correlations
OMIM 602784
UniProt O00230
Pfam PF03002
Entrez Gene 1325
Kegg hsa:1325
References
UniProt :accession O00230
Component-of
clioquinol/cortisol/cortistatin