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high affinity copper uptake protein 1; copper transporter 1; hCTR1; solute carrier family 31 member 1 (SLC31A1, COPT1, CTR1)
Function:
- role in high-affinity copper uptake
Structure:
- homotrimer
- O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain
- belongs to the SLC31A transporter family
Compartment: membrane (probable)
General
copper transporter
glycoprotein
solute carrier family 31 (SLC31, SLC31A)
transmembrane 3 protein
Properties
SIZE: entity length = 190 aa
MW = 21 kD
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-61}
MOTIF: N-glycosylation site {N15}
Thr glycosylation site {T27}
transmembrane domain {62-82}
cytoplasmic loop {83-132}
transmembrane domain {133-153}
exoplasmic loop {154-156}
transmembrane domain {157-177}
cytoplasmic domain {178-190}
Database Correlations
OMIM 603085
UniProt O15431
Pfam PF04145
Kegg hsa:1317
References
UniProt :accession O15431