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COPII coat
Function:
1) covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi
2) acts in the cytoplasm to promote transport of secretory, plasma membrane, & vacuolar proteins from ER to Golgi
Structure:
- subunits: (at least 5)
- Sec23 (SEC23A, SEC23B)
- Sec24 (SEC24A, SEC24C, SEC24D)
- Sec13
- Sec31
- Sar1
Compartment: cytoplasm, perinuclear region
Expression:
- ubiquitously expressed, with higher amounts in placenta, pancreas, heart, liver
General
molecular complex
Properties
SUBUNITS: SEC23
SEC24
SAR1
SEC31
SEC13-related protein
MOTIF: WD repeat {10-49}
WD repeat {54-95}
WD repeat {100-143}
WD repeat {147-203}
WD repeat {209-252}
WD repeat {259-298}
References
UniProt :accession O94855
Components
SEC13-related protein; SEC13-like protein 1 (SEC13L1, SEC13R, SEC13)