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contactin-associated protein-like 3; cell recognition molecule Caspr3 (CNTNAP3, CASPR3, KIAA1714)
Structure:
- belongs to the neurexin family
- contains 2 EGF-like domains
- contains 1 F5/8 type C domain
- contains 1 fibrinogen C-terminal domain
- contains 4 laminin G-like domains
Compartment:
- isoform 1: cell membrane
- isoform 2: secreted
Alternative splicing: named isoforms=2
General
contactin-associated protein
membrane protein
Properties
SIZE: MW = 141 kD
entity length = 1288 aa
COMPARTMENT: cytoplasm
MOTIF: F5/8 TYPE C {31-177}
MOTIF: cysteine residue {C31}
MODIFICATION: cysteine residue {C177}
serine-rich region {42-48}
MOTIF: serine residue (SEVERAL)
cysteine residue {C177}
MODIFICATION: cysteine residue {C31}
LAMININ G-LIKE {183-545} (4)
MOTIF: N-glycosylation site {N285}
cysteine residue {C332}
MODIFICATION: cysteine residue {C364}
N-glycosylation site {N359}
cysteine residue {C364}
MODIFICATION: cysteine residue {C332}
EGF domain {551-996} (2)
MOTIF: cysteine residue {C551}
MODIFICATION: cysteine residue {C562}
cysteine residue {C556}
MODIFICATION: cysteine residue {C571}
cysteine residue {C562}
MODIFICATION: cysteine residue {C551}
cysteine residue {C571}
MODIFICATION: cysteine residue {C556}
cysteine residue {C573}
MODIFICATION: cysteine residue {C583}
cysteine residue {C583}
MODIFICATION: cysteine residue {C573}
transmembrane domain {1246-1266}
Database Correlations
OMIM 610517
UniProt Q9BZ76
PFAM correlations
Entrez Gene 79937
Kegg hsa:79937
References
UniProt :accession Q9BZ76