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conserved oligomeric Golgi complex

Function: - specifically recognizes or associates clathrin-coated vesicles with the trans-GOLGI

Related

gamma-2 adaptin; AP-1 complex subunit gamma-like 2; G2ad (AP1G2)

General

molecular complex

Properties

COMPARTMENT: clathrin coated vesicle SUBUNITS: oligomeric Golgi complex 1 MOTIF: membrane region oligomeric Golgi complex 2 MOTIF: membrane region oligomeric Golgi complex 3 MOTIF: Ser phosphorylation site {S533} oligomeric Golgi complex 4 MOTIF: membrane region oligomeric Golgi complex 5 MOTIF: Ser phosphorylation site {S197} oligomeric Golgi complex 6 MOTIF: membrane region oligomeric Golgi complex 7 MOTIF: membrane region oligomeric Golgi complex 8 MOTIF: membrane region

References

  1. Serafini T et al A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin. Nature. 1991 Jan 17;349(6306):215-20. PMID: 1898984
  2. Morris SA, Mann A, Ungewickell E. Analysis of 100-180-kDa phosphoproteins in clathrin-coated vesicles from bovine brain. J Biol Chem. 1990 Feb 25;265(6):3354-7. PMID: 1968063

Components

conserved oligomeric Golgi complex component 1 (COG1, low density lipoprotein receptor defect B-complementing protein, LDLB, KIAA1381) conserved oligomeric Golgi complex component 2 (COG2, low density lipoprotein receptor defect C-complementing protein) conserved oligomeric Golgi complex component 3 (vesicle docking protein SEC34 homolog, p94, COG3, SEC34) conserved oligomeric Golgi complex component 4 (COG4) conserved oligomeric Golgi complex component 5 (COG5, 13S Golgi transport complex 90 kD subunit, GTC-90, Golgi transport complex 1) conserved oligomeric Golgi complex component 6 (COG6, KIAA1134) conserved oligomeric Golgi complex component 7 (COG7) conserved oligomeric Golgi complex component 8 (COG8)