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conditioned fear response
Pathology:
- behavior modification in which a subject is conditioned (generally inadvertantly) to respond with fear to a previously neutral stimulus
- process involves the amygdala via its connections to the medial prefrontal cortex
- oxytocin enhances fear extinction by upregulating the medial prefrontal cortex inhibition of fear responses in the amygdala [1]
- the conditioned fear response may play a role in PTSD
Related
classical conditioning
General
associative memory/learning (conditioning)
References
- Eckstein M et al.
Oxytocin facilitates the extinction of conditioned fear in
humans.
Biol Psychiatry 2014 Oct 29
PMID: 25542304
http://www.biologicalpsychiatryjournal.com/article/S0006-3223%2814%2900795-1/abstract