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complement factor H-related protein 5 (FHR-5, CFHR5, CFHL5, FHR5)
Function:
1) role in complement regulation
2) binds C3b in vitro
Structure:
- contains 9 Sushi domains (CCP/SCR)
Compartment: secreted
Expression:
- expressed by liver & secreted in plasma
General
glycoprotein
secreted protein
Properties
SIZE: MW = 64 kD
entity length = 569 aa
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-18}
Sushi domain {23-569} (9)
MOTIF: cysteine residue {C87}
MODIFICATION: cysteine residue {C129}
cysteine residue {C114}
MODIFICATION: cysteine residue {C140}
N-glycosylation site {N126}
cysteine residue {C129}
MODIFICATION: cysteine residue {C87}
cysteine residue {C140}
MODIFICATION: cysteine residue {C114}
Database Correlations
OMIM 608593
UniProt Q9BXR6
Pfam PF00084
References
UniProt :accession Q9BXR6