collectin

Function: - component of the innate immune system - can bind to carbohydrate antigens of microorganisms & inhibit their infection by direct neutralization & agglutination, the activation of complement through the lectin pathway, & opsonization by collectin receptors Structure: - C-type lectin superfamily - collagen-like sequences - carbohydrate recognition domains

Specific

collectin-10 (collectin liver protein 1, CL-L1, collectin-34, COLEC10, CLL1, UNQ366/PRO702) collectin-11 (collectin kidney protein 1, CL-K1, COLEC11) collectin-12 (collectin placenta protein 1, CL-P1, hCL-P1, nurse cell scavenger receptor 2, scavenger receptor with C-type lectin, scavenger receptor class A member 4, COLEC12, CLP1, NSR2, SCARA4, SRCL) mannose-binding protein C; MBP-C; MBP1; mannan-binding protein; mannose-binding lectin (MBL2, MBL)

References

- Ohtani K et al, Molecular cloning of a novel human collectin from liver (CL-L1). J Biol Chem. 1999 May 7;274(19):13681-9. PMID: 10224141