collagenase-4 or gelatinase

At least 2 forms Function: - specifically cleaves type IV collagen (basement membrane) - metastatic potential of transformed cells correlates with collagenase-4 activity

Specific

matrix metalloproteinase-2 (matrixin-2, TBE-1, 72 kD gelatinase, gelatinase A, MMP2, CLG4A) matrix metalloproteinase-9 (matrixin-9, 92 kD gelatinase, gelatinase-B, MMP9, CLG4B)

General

collagenase metalloprotein

Properties

COMPARTMENT: extracellular compartment MOTIF: active site metal ion-binding site

References

OMIM :accession 120360