CD300E (CMRF35-like molecule 2, CLM-2, CMRF35-A5, CD300 antigen-like family member E, immune receptor expressed on myeloid cells 2, IREM-2, CD300e antigen, CD300LE, CLM2, CMRF35A5, IREM2)

Function: - probably acts as an activating receptor - interacts with TYROBP - N-glycosylated Structure: - belongs to the CD300 family - contains 1 Ig-like V-type domain (immunoglobulin-like) domain Compartment: cell membrane Expression: - present on the surface of mature hematopoietic cells of the monocyte & myeloid lineages (at protein level)

General

CD300 family protein glycoprotein receptor

Properties

SIZE: entity length = 205 aa MW = 23 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-17} immunoglobulin superfamily domain {18-120} MOTIF: cysteine residue {C36} MODIFICATION: cysteine residue {C104} cysteine residue {C104} MODIFICATION: cysteine residue {C36} N-glycosylation site {N154} transmembrane domain {174-194}

Database Correlations

UniProt Q496F6 Pfam PF07686 Kegg hsa:3425

References

UniProt :accession Q496F6