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Clostridium difficile vaccine; Clostridioides difficile vaccine
Indications:
- investigational prevention of C difficile colitis
Dosage:
- 4 dose series: 0, 1, 6 & 12 monts
Mechanism of action:
- antibody elicited to inactivated C difficile toxin A & C difficile toxin B
General
vaccine
References
- Remich S et al.
A phase 2 extension study evaluating the immunogenicity, safety, and tolerability
of 3 or 4 doses of a Clostridioides difficile vaccine in healthy US adults 65 to
85 years of age.
J Infect Dis 2023 Aug 2; [e-pub].
PMID: 37531657
https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad307/7235954