Search
claudin-like protein 24 (CLP24, TMEM204, C16orf30, UNQ6509/PRO21434)
Function:
- can influence paracellular permeability
- appears to be involved in cell-cell interactions through adherens junction
Compartment:
- cell junction, adherens junction
- co-localizes with the beta-catenin adherins
Expression:
- highly expressed in lung, heart, kidney & placenta
- lower expression in thymus, spleen, liver, testis & ovary
- expressed in endothelial & restricted epithelial cell populations
- induced by hypoxia
Related
claudin-24 (CLDN24)
General
claudin
glycoprotein
Properties
SIZE: MW = 25 kD
entity length = 226 aa
COMPARTMENT: cellular membrane
MOTIF: cytoplasmic domain {1-5}
transmembrane domain {6-26}
exoplasmic loop {27-103}
transmembrane domain {104-124}
cytoplasmic loop {125-136}
transmembrane domain {137-157}
exoplasmic loop {158-170}
MOTIF: N-glycosylation site {N164}
transmembrane domain {171-191}
cytoplasmic domain {192-226}
Database Correlations
UniProt Q9BSN7
References
UniProt :accession Q9BSN7