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chronic idiopathic neutropenia; benign ethnic neutropenia
Epidemiology:
- blacks, Sephardic Jews, West Indians, Arabs of Middle East
Pathology:
- subpopulations of suppressor T-cells that suppress granulopoiesis have been described
- good bone marrow reserve
- patients are not prone to developing infections [2]
Laboratory:
- complete blood count (CBC)
- neutropenia 1000-1500/uL [2]
* detailed workup usually not indicated Differential diagonsis:
- cyclic neutropenia (risk of infections during nadir) [2]
Management:
- not treatment or follow-up needed
General
neutropenia
chronic hematologic disease (chronic blood disorder)
References
- Saunders Manual of Medical Practice, Rakel (ed),
WB Saunders, Philadelphia, 1996, pg 587-89
- Medical Knowledge Self Assessment Program (MKSAP) 18, 19.
American College of Physicians, Philadelphia 2018, 2022