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chromobox protein homolog 8; polycomb 3 homolog; Pc3; hPc3; rectachrome 1 (CBX8 PC3 RC1)
Function:
- component of polycomb group (PcG) multiprotein PRC1 complex
- interacts with MLLT3 & histone H3
Structure: contains 1 chromo domain
Compartment: nucleus
General
chromobox protein homolog
phosphoprotein
Properties
SIZE: entity length = 389 aa
MW = 43 kD
COMPARTMENT: cell nucleus
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
Ser phosphorylation site {S4}
chromodomain
NAME: chromodomain
SITE: 11-69
FOR-BINDING-OF: heterochromatin
Ser phosphorylation site {S110}
Ser phosphorylation site {S130}
Ser phosphorylation site {S256}
Ser phosphorylation site {S265}
Ser phosphorylation site {S311}
Ser phosphorylation site {S332}
Ser phosphorylation site {S352}
Database Correlations
UniProt Q9HC52
Pfam PF00385
Entrez Gene 57332
Kegg hsa:57332
References
UniProt :accession Q9HC52
Component-of
Polycomb group multiprotein PRC1 complex (PcG PRC1 complex, hPRC-H, PcG repressive complex 1)