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chlorprothixene (Taractan, Tarasan, Minithixen, Truxal)
Tradename: Taractan.
Dosage: 25-50 mg PO/IM TID/QID
Tabs: 10, 25, 50, 100 mg
Liquid: 100 mg/5 mL
Adverse effects:
1) sedation
2) extrapyramidal effects
3) hypotension
4) hepatic dysfunction, eosinophilia, leukopenia & thrombocytopenia have been reported
Laboratory:
1) specimen: serum
2) methods: colorimetric
3) interferences:
a) spectrophotometric method lacks sensitivity
b) fluorescence methods also measure metabolites
Interactions
drug interactions
drug adverse effects (more general classes)
General
antipsychotic agent
thioxanthene
Properties
MISC-INFO: elimination route LIVER
KIDNEY
1/2life 8-12 HOURS
therapeutic-range 40-100 NG/ML
toxic-range >100 NG/ML
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,
W.B. Saunders, 1995