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chlamydia rapid test
Indications:
- Chlamydia
Clinical significance:
- specificity 99%, sensitivity 84% for Chlamydia infection
- positive predictive value 87%, negative predictive value 99%
Procedure:
- self-collected vaginal swab
- test results in 30 minutes - 2 hours
- 3 reagents 400 uL, 300 uL, 100 uL premeasured added to swab in sample preparation tube, gentle mixing by hand between additions
- tube capped & used as a dropper to deliver 5 drops (~ 100 uL) to a tube containing lyophylized amplification & detection reagents
- mixed until clear pink solution, then test strip coated with monoclonal antibody to Chlamydial lipopolysaccharide & including control
- solution allowed to stand for 25 minutes before reading result
- appearance of a line on the test strip indicates presence of Chlamydia
- procedure may be repeated on swab to ensure extraction of antigen from viscous vaginal swab
General
point of care test
References
- Mahilum-Tapay L et al,
New point of care Chlamydia Rapid Test - Bridging the gap
between diagnosis and treatment: Performance evaluation study.
BMJ 2007, 335:1190
PMID: 18055487