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cetirizine (Zyrtec, Alertisin, Reactine, Zerviate)

Tradename: Zyrtec, Reactine in Canada (low-sedating antihistamine) over-the-counter in 2008 (pending) 1/08 [2] Dosage: 5-10 mg PO QD Tabs: 5, 10 mg Syrup: 5 mg/5mL Ophthalmic 0.24% (Zerviate): 1 drop OU BID [4] Pharmacokinetics: - onset of action: 1 hour Mechanism of action: - H1 receptor antagonist

Interactions

drug adverse effects of H1 receptor antagonists

Specific

levocetirizine (Xyzal)

General

H1 receptor antagonist (antihistamine)

Properties

MISC-INFO: elimination route LIVER KIDNEY pregnancy-category ? safety in lactation ?

Database Correlations

PUBCHEM correlations

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Prescriber's Letter 15(1): 2008 FDA Approves Zyrtec / Zyrtec-D for Over-the-counter (OTC) Use Detail-Document#: 240110 (subscription needed) http://www.prescribersletter.com
  3. Prescriber's Letter 15(7): 2008 Comparison of Antihistamines Detail-Document#: 240707 (subscription needed) http://www.prescribersletter.com
  4. Brooks M. FDA Clears Cetirizine Eye Drops for Allergic Conjunctivitis, Medscape - Jun 01, 2017 http://www.medscape.com/viewarticle/880989

Component-of

cetirizine/pseudoephedrine cetirizine/pseudoephedrine/tec kinase