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cervicitis

Etiology: 1) Chlamydia trachomatis 2) Neisseria gonorrhoeae 3) idiopathic Clinical manifestations: 1) most women are asymptomatic 2) vaginal discharge - yellow exudate from the endocervical canal 3) vaginal mucosa is normal 3) inflamed & friable cervic 4) vaginal bleeding, especially after sexual intercourse 5) dysuria may occur [1] 6) whiff test negative Laboratory: 1) cervical exudate gram stain - increased numbers of neutrophils 2) Neisseria gonorrhoeae DNA & Chlamydia trachomatis DNA 3) vaginal fluid pH = 5 (case presentation) [1] Management: 1) ceftriaxone 250 mg IM once & doxycycline 100 mg BID for 7 days for treatment of both chlamydia & primary gonorrhea [1] 2) ceftriaxone 250 mg IM once & azithromycin 1 g (single oral dose) if patient unlikely to comply with days of doxycycline [1] 3) cefixime 400 mg & doxycycline 100 mg BID for 7 days if ceftriaxone is unavailable 4) treat sexual partner

Related

Chlamydia trachomatis Neisseria gonorrhoeae (gonococcus, GC)

General

pelvic inflammatory disease (PID) sexually-transmitted disease; sexually-transmitted infection; venereal disease (STD, STI)

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 11,16,17,19. American College of Physicians, Philadelphia 1998,2012,2015,2022.
  2. Centers for Disease Control and Prevention (CDC) Cephalosporin susceptibility among Neisseria gonorrhoeae isolates - United States, 2000-2010. MMWR Morb Mortal Wkly Rep. 2011 Jul 8;60(26):873-7. PMID: 21734634
  3. Wilson JF. In the clinic. Vaginitis and cervicitis. Ann Intern Med. 2009 Sep 1;151(5):ITC3-1-ITC3-15 PMID: 19721016