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cerebellar degeneration-related antigen 1; CDR34 (CDR1)
Expression:
- brain
- predominantly expressed in normal neuroectodermal tissues & in certain malignant tumors
Pathology:
- autoantibodies against CDR1 are found in patients with paraneoplastic cerebellar degeneration
Related
anti-Purkinje cell antibody (anti-Yo)
cerebellar degeneration-related protein 2; paraneoplastic cerebellar degeneration-associated antigen; major Yo paraneoplastic antigen (CDR2, PCD17)
paraneoplastic cerebellar degeneration
General
antigen
other protein
Properties
SIZE: entity length = 262 aa
MW = 31 kD
MOTIF: 23 X 6 AA ~ repeats {3-140}
MOTIF: consensus repeat {3-8}
consensus repeat {9-14}
consensus repeat {15-20}
consensus repeat {21-26}
consensus repeat {27-32}
consensus repeat {33-38}
consensus repeat {39-44}
consensus repeat {45-50}
consensus repeat {51-56}
consensus repeat {57-62}
consensus repeat {63-68}
consensus repeat {69-74}
consensus repeat {75-80}
consensus repeat {81-86}
consensus repeat {87-92}
consensus repeat {93-98}
consensus repeat {99-104}
consensus repeat {105-110}
consensus repeat {111-116}
consensus repeat {117-122}
consensus repeat {123-128}
consensus repeat {129-134}
consensus repeat {135-140}
6 X 6 AA ~ repeats {141-176}
MOTIF: consensus repeat {141-146}
consensus repeat {147-152}
consensus repeat {153-158}
consensus repeat {159-164}
consensus repeat {165-170}
consensus repeat {171-176}
5 X 6 AA ~ repeats {177-206}
MOTIF: consensus repeat {177-182}
consensus repeat {183-188}
consensus repeat {189-194}
consensus repeat {195-200}
consensus repeat {201-206}
Database Correlations
OMIM 302650
UniProt P51861
Entrez Gene 1038
Kegg hsa:1038
References
- UniProt :accession P51861
- OMIM :accession 302650