Centrosome & spindle pole-associated protein 1 (CSPP1, CSSP)

Function: - may play a role in cell-cycle-dependent microtubule organization - phosphoryated - phosphorylation increases in colcemide-treated cells Compartment: - centrosome - associated with mitotic spindles Alternative splicing: named isoforms=2 Expression: - detected in testis - expression of isoform 1 increases throughout the cell cycle & peaks in G2/M phase - expression of isoform 2 is highest in G1 phase & decreases thereafter

General

cytoskeletal protein phosphoprotein

Properties

SIZE: MW = 142 kD entity length = 1221 aa COMPARTMENT: cytoplasm MOTIF: coiled coil {38-62} coiled coil {209-235} coiled coil {382-414} proline-rich region SITE: 443-506 MOTIF: proline residue (SEVERAL) coiled coil {590-634} coiled coil {739-827} coiled coil {890-929}

References

UniProt :accession Q1MSJ5