cell division cycle-associated protein 4; hematopoietic progenitor protein (CDCA4, HEPP)

Function: - may participate in regulation of cell proliferation through the E2F/RB pathway - may be involved in molecular regulation of - hematopoietic stem cells - progenitor cell lineage commitment - differentiation Structure: contains 1 SERTA domain Compartment: nucleus Expression: - highest expression in the pancreas, thymus, testis, spleen, liver, placenta & leukocytes. - lesser expression in lung, kidney, prostate, ovary, small intestine & colon - hardly detectable, if at all, in the brain, skeletal muscle & heart - induced by E2F1

Properties

SIZE: entity length = 241 aa MW = 26 kD COMPARTMENT: cell nucleus MOTIF: SERTA {30-77}

Database Correlations

OMIM 612270 UniProt Q9BXL8 Pfam PF06031 Entrez Gene 55038 Kegg hsa:55038

References

UniProt :accession Q9BXL8