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cell adhesion molecule 2 (immunoglobulin superfamily member 4D, nectin-like protein 3, CADM2, IGSF4D, NECL3)
Structure:
- belongs to the nectin family
- contains 2 Ig-like C2-type domains (immunoglobulin-like)
- contains 1 Ig-like V-type domain (immunoglobulin-like)
Compartment: membrane
Alternative splicing: named isoforms=3
Related
CD62E, E-selectin; endothelial leukocyte adhesion molecule 1; ELAM-1; leukocyte-endothelial cell adhesion molecule 2; LECAM2; CD62 antigen-like family member E (SELE, ELAM1)
neural cell adhesion molecule 2; N-CAM 2 (NCAM2 NCAM21)
General
adhesion receptor
glycoprotein
immunoglobulin superfamily protein
Properties
SIZE: MW = 48 kD
entity length = 435 aa
COMPARTMENT: plasma membrane
MOTIF: signal sequence {1-24}
immunoglobulin superfamily domain {27-119}
MOTIF: N-glycosylation site {N31}
cysteine residue {C44}
MODIFICATION: cysteine residue {C104}
N-glycosylation site {N51}
cysteine residue {C104}
MODIFICATION: cysteine residue {C44}
immunoglobulin superfamily domain {127-219}
MOTIF: cysteine residue {C146}
MODIFICATION: cysteine residue {C203}
cysteine residue {C203}
MODIFICATION: cysteine residue {C146}
immunoglobulin superfamily domain {227-312}
MOTIF: cysteine residue {C248}
MODIFICATION: cysteine residue {C296}
N-glycosylation site {N291}
cysteine residue {C296}
MODIFICATION: cysteine residue {C248}
threonine-rich region {319-350}
MOTIF: threonine residue (SEVERAL)
transmembrane domain {368-388}
Database Correlations
UniProt Q8N3J6
PFAM correlations
References
UniProt :accession Q8N3J6