cell division cycle protein 27 homolog; CDC27Hs; H-NUC (CDC27, D0S1430E, D17S978E)

Function: - phosphorylated - phosphorylation on Ser-426 & Thr-446 occurs specifically during mitosis - interacts with RB protein Structure: - belongs to the APC3/CDC27 family - contains 9 TPR repeats Compartment: nucleus

General

nuclear protein phosphoprotein

Properties

SIZE: entity length = 824 aa MW = 92 kD COMPARTMENT: cell nucleus MOTIF: tetratricopeptide repeat {84-114} tetratricopeptide repeat {115-148} Thr phosphorylation site {T205} Thr phosphorylation site {T209} Thr phosphorylation site {T244} Ser phosphorylation site {S291} Thr phosphorylation site {T313} Ser phosphorylation site {S339} Ser phosphorylation site {S426} Thr phosphorylation site {T430} Ser phosphorylation site {S435} Ser phosphorylation site {S438} Thr phosphorylation site {T446} tetratricopeptide repeat {499-532} tetratricopeptide repeat {567-600} tetratricopeptide repeat {602-634} tetratricopeptide repeat {635-668} tetratricopeptide repeat {670-702} tetratricopeptide repeat {704-736} tetratricopeptide repeat {737-770}

Database Correlations

OMIM 116946 UniProt P30260 Pfam PF00515 Entrez Gene 996 Kegg hsa:996