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CD8B; T-cell surface glycoprotein CD8 beta chain (CD8B1)
Function:
- beta subunit of C8
- phosphorylated as a consequence of T-cell activation
Structure: contains 1 Ig-like V-type domain (immunoglobulin-like)
Compartment:
- cell membrane
- isoform 3: secreted (probable)
Alternative splicing: named isoforms=5
General
glycoprotein
membrane protein
phosphoprotein
protein subunit
Properties
SIZE: entity length = 210 aa
MW = 24 kD
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-21}
immunoglobulin superfamily domain {22-132}
MOTIF: cysteine residue {C41}
MODIFICATION: cysteine residue {C116}
N-glycosylation site {N102}
cysteine residue {C116}
MODIFICATION: cysteine residue {C41}
transmembrane domain {171-191}
Tyr phosphorylation site {Y209}
Database Correlations
OMIM 186730
UniProt P10966
Pfam PF07686
Entrez Gene 926
Kegg hsa:926
References
- UniProt :accession P10966
- Wikipedia; Note: CD8 entry
http://en.wikipedia.org/wiki/CD8
Component-of
CD8