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CD160 antigen; natural killer cell receptor BY55 (CD160, BY55)
Function:
- receptor showing broad specificity for both classical & non-classical MHC class I molecules
Structure:
- homomultimer, disulfide-linked
- contains 1 Ig-like V-type domain (immunoglobulin-like)
Compartment: cell membrane; lipid-anchor, GPI-anchor
Expression:
- expressed in spleen, peripheral blood, & small intestine
- expression is restricted to functional NK cells & cytotoxic T-cells
General
cluster-of-differentiation antigen; cluster designation antigen; CD antigen
cell surface receptor
glypiated protein
immunoglobulin superfamily protein
Properties
SIZE: entity length = 181 aa
MW = 20 kD
COMPARTMENT: plasma membrane
CELL-REGION: apical region
CELL: epithelial cell
MOTIF: signal sequence {1-26}
immunoglobulin superfamily domain {27-122}
MOTIF: N-glycosylation site {N28}
cysteine residue {C44}
MODIFICATION: cysteine residue {C112}
cysteine residue {C61}
MODIFICATION: cysteine residue {C68}
cysteine residue {C68}
MODIFICATION: cysteine residue {C61}
cysteine residue {C112}
MODIFICATION: cysteine residue {C44}
N-glycosylation site {N137}
glycosyl phosphatidylinositol [GPI] membrane anchor {N159}
Database Correlations
OMIM 604463
UniProt O95971
Entrez Gene 11126
Kegg hsa:1112
References
- UniProt :accession O95971
- Entrez Gene :accession 11126