Search
killer cell immunoglobulin-like receptor 3DL3; killer cell inhibitory receptor 1; CD158 antigen-like family member Z; CD158z (KIR3DL3, CD158Z, KIR3DL7, KIRC1)
Function:
- receptor on natural killer cells
- may inhibit activity of NK cells thus preventing cell lysis
Structure:
- belongs to the immunoglobulin superfamily
- contains 3 Ig-like C2-type domain (immunoglobulin-like)
Compartment: cell membrane
General
CD158
glycoprotein
killer cell immunoglobulin like receptor 3DL (KIR3DL)
Properties
SIZE: entity length = 410 aa
MW = 45 kD
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-25}
immunoglobulin superfamily domain {42-97}
MOTIF: cysteine residue {C49}
MODIFICATION: cysteine residue {C95}
cysteine residue {C95}
MODIFICATION: cysteine residue {C49}
immunoglobulin superfamily domain {137-197}
MOTIF: cysteine residue {C144}
MODIFICATION: cysteine residue {C195}
N-glycosylation site {N179}
cysteine residue {C195}
MODIFICATION: cysteine residue {C144}
immunoglobulin superfamily domain {237-295}
MOTIF: N-glycosylation site {N239}
cysteine residue {C244}
MODIFICATION: cysteine residue {C293}
N-glycosylation site {N273}
cysteine residue {C293}
MODIFICATION: cysteine residue {C244}
transmembrane domain {323-343}
Database Correlations
OMIM 610095
UniProt Q8N743
Pfam PF00047
Entrez Gene 115653
Kegg hsa:1156
References
- UniProt :accession Q8N743
- Entrez Gene :accession 115653