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CCR5 antagonist
Indications:
- adjunctive treatment of HIV1
Mechanism of action:
- inhibits entry of HIV1 into cells when HIV1 uses CCR5 to gain entry into cells (50-60% of HIV1 strains)
Interactions
drug interactions
drug adverse effects of antiretroviral agents
Related
C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5; HIV-1 fusion coreceptor; CHEMR13; sCD195 (CCR5, CMKBR5)
Specific
maraviroc (Selzentry)
General
antiretroviral agent
receptor antagonist
References
Prescriber's Letter 14(9): 2007
New Drug: Selzentry (Maraviroc)
Detail-Document#: 230904
(subscription needed) http://www.prescribersletter.com