Cbp/p300-interacting transactivator 2; MSG-related protein 1; MRG-1; P35srj (CITED2, MRG1)

Function: - interferes with the binding of transcription factors HIF-1a & STAT2 to p300/CBP - binds to the p300/CBP CH1 region Structure: belongs to the CITED family Compartment: nucleus Alternative splicing: named isoforms=2 Expression: induced by hypoxia & deferoxamine

Properties

SIZE: entity length = 270 aa MW = 28 kD COMPARTMENT: cell nucleus MOTIF: histidine-rich region {21-57} MOTIF: histidine residue (SEVERAL) glycine-rich region {162-199} acidic region {219-258} MOTIF: acidic residue (SEVERAL)

Database Correlations

OMIM 602937 UniProt Q99967 Pfam PF04487 Entrez Gene 10370 Kegg hsa:10370

References

UniProt :accession Q99967