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cathepsin-G (CTSG)
Function:
- specificity similar to chymotrypsin C
Structure:
- belongs to the peptidase S1 family
- contains 1 peptidase S1 domain
Laboratory:
- cathepsin G antibody in serum
General
cathepsin
glycoprotein
serine protease trypsin family
Properties
SIZE: entity length = 255 aa
MW = 29 kD
COMPARTMENT: lysosome
MOTIF: signal sequence {1-18}
S1 domain {21-243}
MOTIF: cysteine residue {C49}
MODIFICATION: cysteine residue {C65}
histidine residue {H64}
cysteine residue {C65}
MODIFICATION: cysteine residue {C49}
N-glycosylation site {N71}
aspartate residue {D108}
cysteine residue {C142}
MODIFICATION: cysteine residue {C207}
cysteine residue {C172}
MODIFICATION: cysteine residue {C186}
cysteine residue {C186}
MODIFICATION: cysteine residue {C172}
serine residue {S201}
cysteine residue {C207}
MODIFICATION: cysteine residue {C142}
Database Correlations
OMIM 116830
UniProt P08311
Pfam PF00089
Entrez Gene 1511
Kegg hsa:1511
ENZYME 3.4.21.20
References
UniProt :accession P08311