cathepsin-C (cathepsinJ, dipeptidyl peptidase-1, DPP-I, DPPI, CTSC, CPPI)

dipeptidyl peptidase-1

General

cathepsin cysteine proteinase; thiol proteinase dipeptidyl peptidase (DPP) glycoprotein

Properties

SIZE: entity length = 463 aa MW = 52 kD COMPARTMENT: lysosome MOTIF: signal sequence {1-24} N-glycosylation site {N29} cysteine residue {C30} MODIFICATION: cysteine residue {C118} N-glycosylation site {N53} cysteine residue {C54} MODIFICATION: cysteine residue {C136} cysteine residue {C118} MODIFICATION: cysteine residue {C30} N-glycosylation site {N119} cysteine residue {C136} MODIFICATION: cysteine residue {C54} cysteine residue {C255} MODIFICATION: cysteine residue {C298} cysteine residue {C258} N-glycosylation site {N276} cysteine residue {C291} MODIFICATION: cysteine residue {C331} cysteine residue {C298} MODIFICATION: cysteine residue {C255} binding site SITE: 302-302 FOR-BINDING-OF: Chloride binding site SITE: 304-304 FOR-BINDING-OF: Chloride; via amide nitrogen cysteine residue {C321} MODIFICATION: cysteine residue {C337} cysteine residue {C331} MODIFICATION: cysteine residue {C291} cysteine residue {C337} MODIFICATION: cysteine residue {C321} binding site SITE: 347-347 FOR-BINDING-OF: Chloride histidine residue {H405} asparagine residue {N427}

Database Correlations

OMIM correlations MORBIDMAP 602365 UniProt P53634 PFAM correlations Entrez Gene 337936 Kegg hsa:1075 ENZYME 3.4.14.1