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cartilage homeoprotein 1 (CART1, ALX1)
Function:
1) role in chondrocyte differentiation (putative)
2) role in cervix development (putative)
3) repressor with rat prolactin promoter in vivo
Structure:
1) belongs to the paired homeobox family
2) contains 1 homeobox DNA-binding domain
- contains 1 OAR domain
Compartment: nucleus
Expression: expressed in cartilage tissue & cervix
General
transcriptional silencer (transcriptional repressor)
Properties
SIZE: MW = 37 kD
entity length = 326 aa
COMPARTMENT: cell nucleus
MOTIF: homeodomain
SITE: 132-191
OAR domain
SITE: 306-319
Database Correlations
OMIM 601527
UniProt Q15699
PFAM correlations
References
UniProt :accession Q15699