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sedoheptulokinase; SHK; carbohydrate kinase-like protein (SHPK, CARKL)
Function:
ATP + sedoheptulose = ADP + sedoheptulose-7-phosphate
Kinetic parameters:
- KM=0.06 mM for sedoheptulose
- pH dependence: optimum pH is 8.5
Structure: belongs to the FGGY kinase family
Compartment: cytoplasm (putative)
Expression:
- expressed in liver, kidney & pancreas > placenta & heart > lung & brain
General
kinase or ATP-phosphotransferase
Properties
SIZE: entity length = 478 aa
MW = 51 kD
COMPARTMENT: cytoplasm
MOTIF: acetylation site
SITE: N-TERMINUS
EFFECTOR-BOUND: acetyl
kinase domain
MOTIF: ATP-binding site
NAME: ATP-binding site
Database Correlations
OMIM 605060
UniProt Q9UHJ6
Pfam PF00370
Entrez Gene 23729
Kegg hsa:23729
ENZYME 2.7.1.14
References
UniProt :accession Q9UHJ6