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Ca+2 signal-modulating cyclophilin ligand; CAML (CAMLG, CAML)
Function:
- likely role in mobilization of Ca+2 via interaction with TCR/CD3 complex
- binds to cyclophilin B
- the N-terminal domain binds to TNFRSF13B/TACI
Compartment: membrane
Expression:
- ubiquitous
- highest expression in brain, testis & ovary
Interactions
molecular events
General
membrane protein
Properties
SIZE: entity length = 296 aa
MW = 33 kD
COMPARTMENT: cellular membrane
MOTIF: cytoplasmic domain {1-189}
transmembrane domain {190-210}
exoplasmic loop {211-240}
transmembrane domain {241-257}
cytoplasmic domain {258-296}
Database Correlations
OMIM 601118
UniProt P49069
Entrez Gene 819
Kegg hsa:819
References
UniProt :accession P49069
Component-of
molecular complex