Contents

Search

calcium gluconate

for calcium supplementation see calcium carbonate 10% solution (90 mg elemental calcium/10 mL ampule) Indications: 1) symptomatic hypocalcemia a) 20 mL (2 ampules) IV over 10 minutes, followed by b) infusion 60 mL of 10% calcium gluconate in 500 mL D5W (1 mg/mL) at 0.5-2.0 mg/kg/hr c) hypocalcemic tetany 2) hyperkalemia & cardiac arrest due to hyperkalemia a) 10 mL (1 ampule) IV over 2-5 minutes b) a 2nd dose may be given after 5 minutes if no response c) slower infusion rates in patients receiving digitalis because of potential hypercalcemia-induced digitalis activity 3) hypermagnesemia: 10-1-20 mL (2 ampules) IV over 10 minutes 4) osteoporosis [4] Contraindications: pregnancy-category :value + safety-in-lactation :value ? Dosage: Injection: 100 mL/mL. 10 mL. Pharmacokinetics: 1) IV: occurs within minutes 2) IV: lasts approximately 1 hour 3) elimination :route kidney Adverse effects: - uncommon (< 1%) - vasodilation, hypotension, bradycardia, cardiac arrhythmias, ventricular fibrillation, syncope, lethargy, coma, mania, erythema, elevated serum amylase, decreased serum Mg+2, hypercalcemia, hypercalciuria, tissue necrosis, muscle weakness

Interactions

drug adverse effects of calclium supplement(s)

Related

Ca+2 gluconate

General

calcium supplement metabolic agent (metabolic modifier)

Database Correlations

PUBCHEM correlations

References

  1. Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 55, 495
  2. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Deprecated Reference
  5. Department of Veterans Affairs, VA National Formulary

Component-of

calcium carbonate/calcium gluconate/vitamin d calcium gluconate/glucose