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calcium EDTA provocative chelation test; chelation mobilization testing
Indications:
- evaluation of chronic lead poisoning when lead levels are within normal limits
Procedure:
- administration of calcium disodium EDTA mobilizes lead deposited in tissues
- lead in urine is then measured
Clinical significance:
- a high urine lead excretion post EDTA suggests elevated total body lead
- Chelation can then be used as therapy
General
provocative clinical test
References
- Medical Knowledge Self Assessment Program (MKSAP) 16,
American College of Physicians, Philadelphia 2012