calcitonin gene-related peptide (CGRP)

CGRP neurons found in association with heart & blood vessels; suggested nociceptive, ingestive, autonomic & endocrine functions; concentrated in human locus ceruleus

Specific

calcitonin gene-related peptide 1; alpha-type CGRP; calcitonin gene-related peptide I; CGRP-I (CALCA, CALC1) calcitonin gene-related peptide 2; beta-type CGRP; beta-CGRP; calcitonin gene-related peptide II; CGRP-II (CALCB, CALC2)

General

secreted peptide vasodilator

Properties

COMPARTMENT: extracellular compartment SIZE: entity length = 29 aa MOTIF: cysteine-rich region {N-TERMINAL} MOTIF: cysteine residue {X+0} MODIFICATION: cysteine residue {X+6} cysteine residue {X+6} MODIFICATION: cysteine residue {X+0} amide SITE: C-TERMINUS SECRETED-BY: neuron

References

OMIM :accession 114160