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cadherin-6 (kidney cadherin, K-cadherin, CDH6)
Function:
- cadherin
Compartment: membrane
Alternative splicing: named isoforms=2
Expression:
- expressed in brain, cerebellum, kidney > lung, pancreas, gastric mucosa
Pathology:
- expressed in certain liver & kidney carcinomas
General
cadherin
glycoprotein
Properties
SIZE: MW = 88 kD
entity length = 790 aa
COMPARTMENT: plasma membrane
MOTIF: signal sequence {1-18}
N-glycosylation site {N49}
cadherin domain {54-159}
cadherin domain {160-268}
MOTIF: N-glycosylation site {N255}
cadherin domain {269-383}
cadherin domain {384-486}
MOTIF: N-glycosylation site {N399}
N-glycosylation site {N437}
N-glycosylation site {N455}
cadherin domain {487-608}
MOTIF: N-glycosylation site {N536}
transmembrane domain {616-636}
Database Correlations
OMIM 603007
UniProt P55285
PFAM correlations
Entrez Gene 1004
Kegg hsa:1004
References
- Entrez Gene :accession 1004
- UniProt :accession P55285