cadherin-10; T2-cadherin (CDH10)

Function: - cadherin Structure: contains 5 cadherin domains Compartment: cell membrane Expression: - predominantly expressed in brain - also found in adult & fetal kidney - very low levels detected in prostate & fetal lung

General

cadherin glycoprotein

Properties

SIZE: MW = 88 kD entity length = 788 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-22} cadherin domain {55-160} cadherin domain {161-269} MOTIF: N-glycosylation site {N256} cadherin domain {270-384} binding site FOR-BINDING-OF: catenin cadherin domain {385-487} MOTIF: N-glycosylation site {N438} N-glycosylation site {N456} cadherin domain {488-606} MOTIF: N-glycosylation site {N534} Ca+2-binding site SITE: C-TERMINAL transmembrane domain {614-634}

Database Correlations

OMIM 604555 UniProt Q9Y6N8 PFAM correlations Entrez Gene 1008 Kegg hsa:1008