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CD79 or B-cell antigen receptor complex-associated protein

Function: - required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes & antigen presentation Subunits: - consists of CD79A & CD79B

General

cluster-of-differentiation antigen; cluster designation antigen; CD antigen glycoprotein multisubunit protein

Properties

COMPARTMENT: plasma membrane MOTIF: glycosylation site membrane region SUBUNITS: B-cell antigen receptor complex-associated protein alpha chain MOTIF: signal sequence {1-32} immunoglobulin superfamily domain {33-116} MOTIF: cysteine residue {C54} MODIFICATION: cysteine residue {C106} N-glycosylation site {N57} N-glycosylation site {N63} N-glycosylation site {N73} N-glycosylation site {N88} N-glycosylation site {N97} cysteine residue {C106} MODIFICATION: cysteine residue {C54} N-glycosylation site {N112} cysteine residue {C119} MODIFICATION: cysteine residue {C136 IN BETA CHAIN} transmembrane domain {144-165} ITAM {177-205} MOTIF: Tyr phosphorylation site {Y188} tyrosine residue {210} Tyr phosphorylation site {Y210} B-cell antigen receptor complex-associated protein beta chain MOTIF: signal sequence {1-28} immunoglobulin superfamily domain {38-138} MOTIF: cysteine residue {C43} MODIFICATION: cysteine residue {C136} cysteine residue {C65} MODIFICATION: cysteine residue {C122} N-glycosylation site {N73} N-glycosylation site {N101} cysteine residue {C122} MODIFICATION: cysteine residue {C65} N-glycosylation site {N127} N-glycosylation site {N128} cysteine residue {C136} MODIFICATION: cysteine residue {C43} cysteine residue {C136} MODIFICATION: cysteine residue {C119 IN ALPHA CHAIN) (POTENTIAL} transmembrane domain {160-180} ITAM {185-213}

References

  1. UniProt :accession P40259
  2. UniProt :accession P11912

Components

CD79A; B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; surface IgM-associated protein; membrane-bound immunoglobulin-associated protein (CD79A, IGA, MB1) CD79B; B-cell antigen receptor complex-associated protein beta chain; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein (B29. IGB)