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zinc finger protein 36, C3H1 type-like 1; butyrate response factor 1; EGF-response factor 1; ERF-1; protein TIS11B (ZFP36L1, BERG36, BRF1, ERF1, RNF162B, TIS11B)
Function:
- probable regulatory protein involved in regulating the response to growth factors
Structure: contains 2 C3H1-type Zn+2 fingers
Compartment: nucleus
General
nuclear protein
phosphoprotein
zinc finger protein
Properties
SIZE: entity length = 338 aa
MW = 36 kD
COMPARTMENT: cell nucleus
MOTIF: Ser phosphorylation site {S54}
Ser phosphorylation site {S92}
Zinc finger
NAME: Zinc finger
SITE: 114-142
EFFECTOR-BOUND: Zn+2
Zinc finger
NAME: Zinc finger
SITE: 152-180
EFFECTOR-BOUND: Zn+2
serine-rich region {307-316}
MOTIF: serine residue (SEVERAL)
Ser phosphorylation site {S334}
Database Correlations
OMIM 601064
UniProt Q07352
PFAM correlations
Entrez Gene 677
Kegg hsa:677
References
- UniProt :accession Q07352
- Atlas of Genetics & Cytogenetics in Oncology & Haematology
http://atlasgeneticsoncology.org/genes/ZFP36L1ID42866ch14q22.html