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bullous lung disease

Etiology: 1) small apicial bullae may be present in the lung apex of normal individuals 2) congenital a) Marfan's syndrome b) Ehlers-Danlos syndrome 3) acquired a) burnt out sarcoidosis b) cadmium exposure 4) panlobular emphysema may appear like bullae Pathology: - lack of air communication with bronchi may cause air trapping Complications: 1) pneumothorax 2) COPD 3) lung abscess 4) hemorrhage into bulla 5) compression of adjacent normal lung Management: - surgery may improve lung function by 5-10% in 10-15% of patients

Related

bulla; bleb Ehlers-Danlos syndrome; cutis elastica (EDS) emphysema Marfan syndrome sarcoidosis

Specific

congenital cystic adenomatoid malformation; congenital pulmonary airway malformation giant bullous emphysema; Vanishing lung syndrome

General

lung disease

References

Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 739-40