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bromodomain-containing protein 1; BR140-like protein; bromodomain & PHD finger-containing protein 2 (BRD1, BRL, BRPF2)
Function:
- component of the MOZ/MORF complex which has histone H3 acetyltransferase activity
Structure:
- contains 1 bromo domain
- contains 1 PHD-type Zn+2 finger
- contains 1 PWWP domain
Compartment: nucleus
Alternative splicing: named isoforms=2
Expression: highly expressed in testis
General
Bromodomain-containing protein
phosphoprotein
zinc finger protein
Properties
SIZE: entity length = 1058 aa
MW = 120 kD
COMPARTMENT: cell nucleus
MOTIF: Ser phosphorylation site {S25}
Ser phosphorylation site {S128}
Zn finger PHD-type
NAME: Zn finger PHD-type
SITE: 214-264
EFFECTOR-BOUND: Zn+2
bromodomain {579-649}
PWWP domain {929-1012}
Thr phosphorylation site {T1051}
Ser phosphorylation site {S1052}
Ser phosphorylation site {S1055}
Database Correlations
OMIM 604589
UniProt O95696
PFAM correlations
Entrez Gene 23774
Kegg hsa:23774
References
UniProt :accession O95696