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Brockenbrough's sign

Etiology: - Brockenbrough's sign is observed in association with hypertrophic cardiomyopathy. Clinical manifestations: - on the beat following a premature ventricular contraction (PVC), the systolic ejection murmur increases in intensity where as the arterial pulse (carotid) volume decreases - this occurs secondary to increased contractility & decreased afterload

Related

hypertrophic cardiomyopathy (HCM), including idiopathic hypertrophic subaortic stenosis (IHSS)

General

sign/symptom

References

Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 106