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BRCA1 promoter methylation in leukocytes

Indication: - assessment of ovarian cancer risk Clinical significance: - BRCA1 promoter methylation in leukocytes is positively associated with risk for high-grade serous ovarian cancer [1]

General

molecular diagnostic test

References

  1. Lonning PE, Berge EO, Bjornslett M et al White Blood Cell BRCA1 Promoter Methylation Status and Ovarian Cancer Risk. Ann Intern Med. 2018 Jan 16. PMID: 29335712